Sinkfingerprotein 687

ZNF687
Identifikatorar
Andre namn	ZNF687, PDB6, zinc finger protein 687
Eksterne ID-ar	OMIM: 610568 MGI: 1925516 HomoloGene: 10827 GeneCards: ZNF687
Genplassering (menneske)
Kromosom	Menneskekromosom 1
Ende	151,292,176 bp
Genplassering (mus)
Kromosom	Musekromosom 3
Ende	95,015,448 bp
RNA-uttrykksmønster
	Top expressed in
	cardia; ; bone marrow cells; ; ventral tegmental area; ; blod; ; brystvorte; ; nucleus subthalamicus; ; luftrøyr; ; monocytt; ; inferior ganglion of vagus nerve; ; ganglionic eminence;
	Meir referanseuttrykksdata
	n/a
Genontologi
Molekylær funksjon	metallionebinding; DNA-binding; GO:0001948, GO:0016582 proteinbinding; nukleinsyrebinding; GO:0001200, GO:0001133, GO:0001201 DNA-binding transcription factor activity, RNA polymerase II-specific;
Sellekomponent	cellekjerne; cytoplasma; nukleoplasma; cytosol;
Biologisk prosess	GO:0009373 regulation of transcription, DNA-templated; transcription, DNA-templated; GO:0044324, GO:0003256, GO:1901213, GO:0046019, GO:0046020, GO:1900094, GO:0061216, GO:0060994, GO:1902064, GO:0003258, GO:0072212 regulation of transcription by RNA polymerase II;
	Kjelder:Amigo / QuickGO
Ortologar
	57592
	78266
	ENSG00000143373
	ENSMUSG00000019338
	Q8N1G0
	Q9D2D7
	NM_001304763; NM_001304764; NM_020832
	NM_030074; NM_001357863
	NP_001291692; NP_001291693; NP_065883
	NP_084350; NP_001344792
	Wikidata
sjå/endra menneske	sjå/endra mus

Sinkfingerprotein 687 er eit protein som hos menneske er koda for av genet ZNF687.^[5]^[6] Det høyrer til underfamilien C2H2 i sinkfingerfamilien.^[7]

Kjelder[endre | endre wikiteksten]

↑ ^1,0 ^1,1 ^1,2 GRCh38: Ensembl release 89: ENSG00000143373 - Ensembl, May 2017
↑ ^2,0 ^2,1 ^2,2 GRCm38: Ensembl release 89: ENSMUSG00000019338 - Ensembl, May 2017
↑ «PubMed-kjelde for menneske:». National Center for Biotechnology Information, U.S. National Library of Medicine.
↑ «PubMed-kjelde for mus:». National Center for Biotechnology Information, U.S. National Library of Medicine.
↑ Nagase T, Kikuno R, Ishikawa KI, Hirosawa M, Ohara O (Apr 2000). «Prediction of the coding sequences of unidentified human genes. XVI. The complete sequences of 150 new cDNA clones from brain which code for large proteins in vitro». DNA Res 7 (1): 65–73. PMID 10718198. doi:10.1093/dnares/7.1.65.
↑ «ZNF687 zinc finger protein 687 [ Homo sapiens (human) ]». Gene. National Center for Biotechnology Information. 4. juni 2017. Henta 2. juli 2017.
↑ Divisato G, Formicola D, Esposito T, Merlotti D, Pazzaglia L, Del Fattore A; et al. (2016). «ZNF687 Mutations in Severe Paget Disease of Bone Associated with Giant Cell Tumor.». Am J Hum Genet 98 (2): 275–86. PMC 4746367. PMID 26849110. doi:10.1016/j.ajhg.2015.12.016.

Bakgrunnsstoff[endre | endre wikiteksten]

Olsen JV, Blagoev B, Gnad F, et al. (2006). «Global, in vivo, and site-specific phosphorylation dynamics in signaling networks.». Cell 127 (3): 635–48. PMID 17081983. doi:10.1016/j.cell.2006.09.026.
Beausoleil SA, Villén J, Gerber SA, et al. (2006). «A probability-based approach for high-throughput protein phosphorylation analysis and site localization.». Nat. Biotechnol. 24 (10): 1285–92. PMID 16964243. doi:10.1038/nbt1240.
Gregory SG, Barlow KF, McLay KE, et al. (2006). «The DNA sequence and biological annotation of human chromosome 1.». Nature 441 (7091): 315–21. PMID 16710414. doi:10.1038/nature04727.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). «The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).». Genome Res. 14 (10B): 2121–7. PMC 528928. PMID 15489334. doi:10.1101/gr.2596504.
Beausoleil SA, Jedrychowski M, Schwartz D, et al. (2004). «Large-scale characterization of HeLa cell nuclear phosphoproteins.». Proc. Natl. Acad. Sci. U.S.A. 101 (33): 12130–5. PMC 514446. PMID 15302935. doi:10.1073/pnas.0404720101.
Ota T, Suzuki Y, Nishikawa T, et al. (2004). «Complete sequencing and characterization of 21,243 full-length human cDNAs.». Nat. Genet. 36 (1): 40–5. PMID 14702039. doi:10.1038/ng1285.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). «Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.». Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. PMC 139241. PMID 12477932. doi:10.1073/pnas.242603899.

[refGRCh38Ensembl-1] 1,0 ^1,1 ^1,2 GRCh38: Ensembl release 89: ENSG00000143373 - Ensembl, May 2017

[refGRCm38Ensembl-2] 2,0 ^2,1 ^2,2 GRCm38: Ensembl release 89: ENSMUSG00000019338 - Ensembl, May 2017

[3] «PubMed-kjelde for menneske:». National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] «PubMed-kjelde for mus:». National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid10718198-5] Nagase T, Kikuno R, Ishikawa KI, Hirosawa M, Ohara O (Apr 2000). «Prediction of the coding sequences of unidentified human genes. XVI. The complete sequences of 150 new cDNA clones from brain which code for large proteins in vitro». DNA Res 7 (1): 65–73. PMID 10718198. doi:10.1093/dnares/7.1.65.

[gene-znf687-6] «ZNF687 zinc finger protein 687 [ Homo sapiens (human) ]». Gene. National Center for Biotechnology Information. 4. juni 2017. Henta 2. juli 2017.

[pmid26849110-7] Divisato G, Formicola D, Esposito T, Merlotti D, Pazzaglia L, Del Fattore A; et al. (2016). «ZNF687 Mutations in Severe Paget Disease of Bone Associated with Giant Cell Tumor.». Am J Hum Genet 98 (2): 275–86. PMC 4746367. PMID 26849110. doi:10.1016/j.ajhg.2015.12.016.

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